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These alterations contribute to systemic inflammation by increasing the production of pro-inflammatory cytokines, including interleukin (IL)-1, IL-6, IL-8, IL-13, tumor necrosis factor-alpha (TNF-), and transforming growth factor-beta 1 (TGF-1) [24]

While we always personalize treatment, heres a general starting point we use when creating a plan: Dosage: 250 to 500 mcg per day Method: Subcutaneous injection near the affected joint Cycle: 4 weeks on, followed by 2 to 4 weeks off Duration: Usually 1 to 3 cycles, depending on severity Injectable BPC-157 is preferred for arthritis

10.1016/j.actbio.2022.11.002 23 ChenP.VilorioN

Regulatory limits on BPA exposure, and practical considerations for reducing exposure [1:12:45]