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Headache and fatigue round out the list
Jennings SV, Finnerty CC, Hobart JS, Martn-Martnez M, Sinclair KA, Slee VM, et al
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Despite advances in diagnostics based on clinical examination, imaging, and biochemical markers (239), effective therapies remain limited
As of September 2023 it is on the FDA's Category 2 list of bulk drug substances that may not be compounded due to significant safety risks, and the agency has scheduled a Pharmacy Compounding Advisory Committee (PCAC) review for July 2026 covering proposed uses in opioid withdrawal, chronic insomnia, and narcolepsy
