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Notably, certain metabolites may exhibit context-dependent functional polarity, where even the same metabolite can produce opposing effects depending on experimental conditions, dosage regimens, or disease stages

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Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial

While standard side effects like temporary swelling, bruising, and localised tenderness are common to all injectables, viral or unregulated treatments carry unique risks