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Lancet (2015) 386(9996):896912
Participants were randomly assigned to receive once daily orforglipron (12, 24, 36, or 45 mg) or placebo for 36 weeks as an adjunct to lifestyle intervention that included education regarding healthy eating and exercise provided by trial personnel
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Counsel patients regarding the potential risk of MTC with use of Saxenda and inform them of symptoms of thyroid tumors (eg, a mass in the neck, dysphagia, dyspnea, persistent hoarseness)
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