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Recently, the pharmacotherapy of MASLD mainly focuses on three parts of mechanisms: anti-inflammatory (ASK1 inhibitors), anti-diabetic (GCGR agonists, PPAR agonists), and prevention of lipotoxicity (FXR agonists, FGF21 analogues) (Wei et al., 2024)
Mild to moderate hypoglycemia is often associated with symptoms such as palpitations, anxiety, confusion, hunger, sweating, agitation, tremors, and paresthesia
Contraindications include active malignancy, uncontrolled diabetes, pregnancy, or history of certain cancers
Gerstein HC, Sattar N, Rosenstock J, for the AMPLITUDE-O Trial Investigators, et al
