To increase power, we conducted a meta-analysis of genome-wide association studies of ovarian cancer (29,066 cases, 461,542 controls), and identified 12 genome-wide associated variants, including two previously unreported variants: rs77247401 ( MIR1208 ) and rs56159231 ( PLEKHM1 )
The mechanism of action involves mimicking two naturally occurring incretin hormones that play crucial roles in glucose regulation and appetite control
Also, evidence was typically based on post hoc analysis or findings not determined a priori in study designs, and thus risk of bias was downgraded
Additional research links BPC-157 to protective effects in the gastrointestinal system under physical stress or medication use
Autophagy 8 , 17691781 (2012)