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Additionally, acetylation modification of the P53 DNA-binding region can regulate SLC7A11 expression, thereby promoting ferroptosis in certain cancer cells [9]

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Alternatively, the more supported hypothesis is that there could be hyper-responsivity of the cholinergic receptors at a hypothalamic level, causing a greater decrease in somatostatin tone, and elevated GH release from the anterior pituitary gland (153)

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