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There can be no guarantees with respect to pipeline candidates that the candidates will receive the necessary regulatory approvals or that they will prove to be commercially successful

In our study, the highest proportion of differential metabolites was found in urine (n=52) compared to plasma (n=32) and hair (n=31) samples

Thus, the conclusions of those studies must be further validated, and a wider range of studies is necessary to ensure the reliability of the findings

Korzun ( Reference Korzun 30 ) studied healthy human subjects of both sexes who received creatine for 28 d and detected a small but significant reduction of Hcy levels compared with controls