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Similarly, both gut-selective and systemically active doses of sitagliptin increased plasma levels of active GLP-1 and reduced TG excursion after olive oil gavage in Dpp4 Gut/ mice (Figure 4, C and D)

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These peptides could represent the next evolution in obesity pharmacotherapytargeting multiple hormone receptors for lasting results.

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They identified changes in tyrosine, tryptophan, and purine pathways in HD, many of which are related to cellular metabolism and oxidative stress (174)

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