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Whilst people with obesity using orlistat lose an extra 2.93.4 kg weight over 12 months, gastrointestinal side effects, reduced absorption of fat-soluble vitamins and steatorrhea are commonplace [9]
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Common side effects of Orlistat compared to placebo include: Abdominal pains Bloating Urgent bowel movements Fatty liquidy oily stools Constipation, diarrhoea Flatulence with an oily discharge If you experience any serious side effects, you should contact NHS 111
Potential cardiovascular benefits : Some studies suggest it may have positive effects on heart health due to improved metabolic markers
Freund H, Hoover HC Jr, Atamian S, et al
Individuals considering taking both supplements should be aware that evidence for the combined use of berberine and L-carnitine is limited
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