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Some increase your appetite, some cause your body to retain more fluid and fat, and some may slow down your metabolism

Bittremieux M, Parys JB, Pinton P, Bultynck GER

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Rare but serious adverse effects include pancreatitis (though causality remains uncertain), gallbladder disease, and potential thyroid C-cell tumors (observed in rodent studies but not conclusively demonstrated in humans)