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These include: Allergic reactions, such as hives or trouble breathing Heart problems in people with heart issues Drug Interactions and Contraindications Vitamin B12 shots can affect how some medicines work or have special warnings

It seems you may need high B12 supplementation and to stop any folate supplements for a while

Cartilage and chondrocyte studies: Emerging research evaluates the compound for proteoglycan and collagen synthesis in articular cartilage models relevant to osteoarthritis

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