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Dihexa uses oral/sublingual dosing of similar mass ranges
Umbareen Mahmood, MD, a board-certified plastic surgeon in New York City, says shes now even encountering men and women with already-low BMIs who are using the drugs to lose a few pounds for a big event or beach vacation. Surprisingly, many of these patients are still seeing negative aesthetic side effects, likely due to how rapid the weight loss wasthose who lose weight gradually tend to have better tissue elasticity and skin retractionand also because their margin for loss is smaller given that they were already at a healthy weight for their body. (When someones BMI is low to start, she explains, losing a few pounds can have a significant impact on the little bit of fat you have.) Jerry Chidester, MD, a board-certified plastic surgeon in Draper, Utah, tells me that close to half of his patients are currently using a GLP-1 or have in the past
Serious adverse effects , whilst rare, include: Pancreatitis : Patients should be advised to discontinue Ozempic immediately and seek urgent medical attention if they experience severe, persistent abdominal pain
Kindregan, D., Gallagher, L
Cardiovasc Hematol Agents Med Chem 16(1):3543 Boland ML, Laker RC, Mather K, Nawrocki A, Oldham S, Boland BB, Lewis H, Conway J, Naylor J, Guionaud S, Feigh M, Veidal SS, Lantier L, McGuinness OP, Grimsby J, Rondinone CM, Jermutus L, Larsen MR, Trevaskis JL, Rhodes CJ (2020) Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis
