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A 2025 review in Cell highlighted the benefit of GLP-1 therapies on anti-inflammatory mechanisms involved in cardiovascular, kidney and liver conditions, and disorders like obstructive sleep apnea

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Compared to basal-bolus insulin therapy, insulin/GLP-1 drugs offer a simple and safe approach to managing titration, Billings said

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The cardiovascular safety of this dose of semaglutide is currently being evaluated in the SELECT trial, where 17,500 individuals with obesity and established CVD are randomised to semaglutide or placebo for 2.5-5 years

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Reducing adipose tissue lowers systemic estrogen, which can reduce stimulation of endometrial implants

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