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Because the results are highly dependant on the patient, we are unable to guarantee a particular outcome
(December 2008)
Moreover, controlled release and targeted delivery can be achieved [64], minimizing toxic side effects [65]
Using CRISPR-Cas9 in human and mouse cells, genome-wide, targeted loss-of-function pooled screens have been studied that has provided information about the inactivated genomic loci and strategies that modulate transcriptional activities (Shalem et al., 2015)
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