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Molecular mechanism-driven discovery of novel small molecule inhibitors against drug-resistant SARS-CoV-2 M(pro) variants

J Am Chem Soc 134:1666216670 McDonald RJ, McDonald JS, Kallmes DF, Jentoft ME, Murray DL, Thielen KR, Williamson EE, Eckel L (2015) Intracranial gadolinium deposition after contrast-enhanced MR imaging

GSH, the most abundant non-protein thiol in cells, acts as a redox buffer to protect cells from oxidative stress and regulate cellular redox signaling, and the thiol group of cysteine in the backbone of GSH is responsible for its antioxidant capacity in maintaining redox homeostasis [36]

LH levels in the second group also increased a bit, but the result was not reported as it was not statistically significant