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( 2 ) In fact, studies have shown that these medications can often have a staggering impact, with large-scale studies showing that patients using semaglutide lost nearly 15 percent of body weight over 68 weeks, compared to just under a 3 percent loss for those using a placebo
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A February 2026 study found an 11% higher fragility fracture risk in GLP-1 users in a specific diabetic population
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