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In the Lira Pump study, they decreased basal insulin by 10%, but increased bolus by 15% ( Our current practice is to consider a ~20% bolus insulin decrease and a ~10% basal insulin decrease before GLP-1RA initiation, although prior A1c, risk of hypoglycemia, potential risk of ketosis due to reduced insulin doses, as well as other patient-specific factors should guide the final insulin dose changes
These medications work by mimicking a hormone your body already produces (glucagon-like peptide-1) which slows digestion, curbs appetite, and helps regulate blood sugar
Medical College of Virginia
It specifically engineers them to avoid the phenomenon of long-term reliance
This timeline is dependent on how quickly the patient is able to increase the dosage of Ozempic, with a higher dosage meaning they will be able to lose more weight in a short amount of time
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