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**Disclaimer: The people interviewed above are not Ro patients and are not affiliated with Ro Health

23 Tissue Dysfunction: Senescent cells accumulate in various tissues as organisms age, including the skin, skeletal muscle, adipose tissue, liver, and vasculature

And when I finished, I was less confident that I knew what was in my water than I had been at the beginning

The Hostynek and Maibach group at UCSF measured exactly this in 2011: human skin permeation of GHK-Cu as a function of skin layer, with the result that the peptide accumulates in the upper stratum corneum but does not pass through to viable epidermis or dermis in any meaningful quantity 4