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Common Side Effects of Tirzepatide and Semaglutide The most frequently reported side effects include: Nausea (particularly during dose increases) Diarrhea or constipation Vomiting Abdominal discomfort Decreased appetite (expected effect) Most side effects occur during dose escalation and typically improve within 4-8 weeks as your body adjusts to the medication

Storage Quick Reference Pro tip: When multiple vials are purchased, documented practice is to keep unopened ones in the freezer and reconstitute only what will be used within 3-4 weeks

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These conditions or factors are referred to as contraindications