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Nat Rev Neurol 7(11):639649

Symptoms appear in infants within four weeks of birth, and diagnosis is based on 5-oxoprolinuria, increased levels of 5-oxoproline in the urine

Glutathione is a key player in Phase II detoxification, a process where the liver attaches a molecule to a toxin to make it water-soluble so it can be excreted

Because sufficient copper is required for stem cells to begin proliferating and repairing tissues and because the GHK tripeptide silences the copper ions oxidative toxicity during transport GHK-Cu enables safe, targeted copper bioavailability at sites that need it most

10.7150/thno.22679 87 ZhouR.WangH.YangY.ZhangC.DongX.DuJ.et al (2019)