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Signs of Correct Administration A successful B12 injection should cause: Minimal pain at the site A small bump that fades within an hour Mild redness or soreness that resolves within 24 hours If symptoms worsen (swelling, pain, fever, rash), consult a doctor immediately

B12 levels in the blood return to normal once all that excess has been urinated

doi:10.1146/annurev.biochem.72.121801.161828

A total of 221 similar patients from another hospital served as the external validation cohort

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