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Genetically enhancing NF-B activity causes neuroinflammation and increases senescent cell burden in the brain (86)
Acute administration of semaglutide, tirzepatide, and retatrutide each attenuated alcohol discrimination across multiple doses, suggesting that blunting or altering subjective alcohol effects could be a common target of this drug class
Thats why working with a healthcare provider to understand your hormone needs is important
So right now it is not approved by the FDA for any human use
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