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This exceptional result highlights its potential as one of the most effective anti-obesity therapies in development, underscoring the therapeutic promise of multi-receptor agonists in weight management
[82] in long COVID), or measuring brain metabolites while participants perform a cognitive task or experience a physiological stimulus such as pain or photostimulation [83]
SGLT2 inhibitors and metformin are often used alongside GLP-1 therapy because they work through distinct mechanisms, offering additional benefits like weight loss and improved cardiovascular health
Second, weight loss had not plateaued at 80 weeks: in a pre-specified extension involving 532 participants with a baseline BMI of 35 or above, those continuing to 104 weeks reached an average of 30.3 per cent
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