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Author Contributions Authors equally contributed to research and preparation of the manuscript
A 1-ml dilution produces a 5 mg/ml solution that is five times the expected concentration
Supplied as a lyophilised solid for stability and straightforward storage
NO can act as a vasodilator, neurotransmitter, and immune response regulator (96)
Effects depend on what the individual is targeting: Immediate (after 1 session): Feeling refreshed Light hydration boost Subtle glow 46 sessions: Noticeable skin clarity More even tone Improved radiance Long-term (8+ sessions): Deeper antioxidant effects Stable brightening Better skin texture and vitality Sun exposure, hydration, and sleep also influence outcomes
