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Rhonda Patrick: Then I started looking at the sequence, and I was doing some in silico work

In summary, age-dependent changes such as increased catalytic iron levels, weakened antioxidant defenses, elevated mitochondrial-derived oxidative stress and sustained membrane vulnerability to peroxidation, collectively place neurons in the aging brain in a fragile state

And as it does, a picture is emerging that looks very familiar to practitioners of functional and integrative medicineone defined by viral persistence, mitochondrial dysfunction, chronic inflammation, immune dysregulation, microbiome disruption, and autonomic nervous system damage

If peptide-based approaches can provide meaningful benefit at lower cost and with fewer side effects, that combination would make them attractive as either standalone or adjunctive therapy

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