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If appetite only appears during certain hours, work with those windows rather than forcing rigid meal schedules

Referral thresholds are broadly guided by NICE but may vary according to local NHS Integrated Care System (ICS) policies

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The samples were vortexed 15 s and left in a freezer at -20 C for 60 min, followed by centrifugation at 21,100 RCF for 15 min at 4 C

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