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Altered metabolic phenotypes, marked by an increased dependency on oxidative phosphorylation (OXPHOS) for adenosine triphosphate (ATP) production over glycolysis, have been noted in PC cells (Massie et al., 2011)
In particular the ability of ESD and EIS scores to produce consistent scores overtime in a stable patient population (test-retest reliability), the extent to which ESD and EIS scores reflect scores for other PROs measuring similar/dissimilar concepts (concurrent validity), are able to discriminate between groups according to key indicators e.g
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As its use has expanded, questions have emerged about potential effects on sexual function, particularly erectile dysfunction (ED)
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