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Apparent k red values were estimated from linear fits at low PfGrx concentrations

It is not approved for human consumption, therapeutic use, or medical diagnosis

Because the final biologic molecules critical quality attributes, including its glycosylation pattern, charge variant distribution, aggregation state, oxidation profile, and deamidation level, emerge directly from cell culture conditions, purification sequences, and formulation choices, two manufacturers producing the same amino acid sequence will not produce identical molecules

Methods Materials All the chemicals were purchased from Sigma-Aldrich or Alfa Aesar unless otherwise specified

FDA Titration vs