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The expression of intestinal endocrine Lcells is regulated by several key receptors activated by short chain fatty acids (SCFAs), specific endogenous cannabinoids and bile acids, and the activation of these receptors increases the secretion of key intestinal peptides, such as GLP-1, GLP-2 and polypeptide YY (PYY) (de Vos et al., 2022)
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Testing of research chemicals reveals alarming contamination and quality issues
Smaller, more frequent meals sit better than large ones because the peptide slows gastric emptying
Nauck MA, Kleine N, Orskov C, Holst JJ, Willms B, Creutzfeldt W
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