semaglutide picture ABOUT AND WEIGHT LOSS SkinnyRx: Injectable Semaglutide (GLP-1)

Some studies indicate these drugs can reduce cocaine self-administration and relapse-like drug seeking

KEY FINDINGS In an eight-week randomized, double-blind, placebo-controlled trial involving 50 adults seeking treatment for moderate-to-severe AUD, participants receiving oral semaglutide showed: Fewer heavy drinking days Reduced alcohol consumption per drinking occasion Lower day-to-day alcohol cravings Fewer alcohol-related problems Improved overall drinking risk level Reduced cannabis use days While not all measures changed in controlled laboratory settings, the overall pattern showed consistent reductions in harmful real-world drinking behavior

The Multifaceted Role of Endothelial Sirt1 in Vascular Aging: An Update

An early meta-analysis suggested that 3 g/day may be necessary to normalize serum ALT in a significant patient proportion (96), while other studies report benefits with 2 g/day on AST, ALT, and HOMA-IR (37)

As mentioned above, it is not definitive that this is indeed a problem for people with IBS and more research is needed to understand this better