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Aged mice were intraperitoneally injected with 5 mg/kg FOXO4-DRI or PBS as a control every other day for three administrations, and effects were assessed 30 days post-treatment
Never inject into the exact same spot within 12 weeks
GSH depletion-dependent cell death was prevented by selective ferroptosis inhibitors (8 M Fer-1 and 600 nM Lip-1), iron chelator DFO (80 M), as well as autophagic inhibitors Baf-A1 (75 nM) and 3-MA (10 mM)
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The 50mg High-Concentration Variant is specifically designed for laboratories conducting extended longitudinal studies or high-volume cell culture assays where larger stock solutions are required
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