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Some people take these medications without ever making a trip to see their doctor, new reports show

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To gain a more comprehensive understanding of the potential clinical applications of NRF2, the following table summarizes relevant clinical trial information

This leads to the accumulation of misfolded or aggregated proteins, the activation of endoplasmic reticulum stress and unfolded protein response, and further aggravation of heat-induced cellular injury (Hetz et al., 2020