To maximise the cardiovascular benefits of GLP-1 RAs at a population level, strategies can be used to improve tolerability, such as patient counselling, gradual dose escalation and the use of long-acting formulations [27]
Amycretins dual agonist mechanism, while targeting fewer receptors, may offer distinct advantages due to its focused approach and potentially better tolerability profile
Analyses were conducted using non-compartmental methods in the statistical software SAS, version 9.4 M5
A nivel mundial, el uso del alcohol es responsable de alrededor de 2.8 millones de muertes al ao y para el ao 2021 la prevalencia del TCA, en personas de 15 aos y ms, fue de 1,335 por cada 100,000 habitantes (Xie et al.,2025)
New or worsening depression should be addressed, as fatigue is a common symptom of mood disorders