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571 In the early stages of the disease, these mediators enhance and prolong inflammatory responses via non-cell-autonomous mechanisms
Less common side effects include hair loss and change or loss in taste
As these nasal cartilages are reshaped, a more symmetric appearance results and the tissues of the columella are straightened and lengthened, lessening the need for more invasive surgical techniques
For these patients, an individualised risk assessment before or shortly after starting treatment is worthwhile
24 These mechanisms may help prevent the development of enthesitis
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