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Ann Thorac Surg 107(3):936-940, 2019
It means the stakes are higher and the decision requires more careful consideration
Based on the disruption of the antioxidant defense system and the accumulation of ROS, lipid peroxide could be formed inside the cancer cell 41
[...] Even though the carboxylic acid valproate (VPA) is an HDACi with weak inhibitory potential, it is an interesting drug for clinical trials due to its well-characterized pharmacodynamic and pharmacokinetic profile (see Table 6)
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