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*All data are sourced from Novo Nordisk STEP trial programs (STEP UP, STEP 4, STEP 5) and the WeGoTogether real-world observational study
Food and Drug Administration (FDA) to help manage Type 2 diabetes, these drugs are now also widely prescribed for weight loss, weight management, and cardiovascular health
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CagriSema: Two Molecules, Complementary Mechanisms CagriSema combines two existing molecules in a fixed-dose injection
Statistical analysis For each study population, the semaglutide cohort and the comparision cohort were propensity-score matched (1:1 using nearest neighbor greedy matching with a caliper of 0.25 times the standard deviation) on covariates that are potential risk factors for AUD 57,58,59,60 including demographics, adverse socioeconomic determinants of health (e.g., problems related to education and literacy, employment and unemployment, housing and economic circumstances, social environment, upbringing, primary support group including family circumstances and various psychosocial circumstances), problems with lifestyle (e.g., tobacco use, lack of physical exercise, inappropriate diet and eating habits, high-risk sexual behavior, gambling and betting, and other problems related to lifestyle including antisocial behaviors and sleep deprivation), pre-existing medical conditions, medications, medical procedures and medical visit types (outpatient, inpatient, emergency, and virtual)
