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Clinical and animal studies have shown that vitamin C supplementation can significantly improve the prognosis of patients with AP, especially in severe cases, by reducing oxidative stress and organ damage (121)

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In the USA and UK, doses ranging from 100 to 1,000 g (0.1 to 1 mg) per month (or every 2-3 months when hydroxocobalamin is given) are used for the duration of the patients life [11]