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589, 963973 J Physiol 2013
For instance, butyrate modulates the immune response to HIV but can also increase HIV-1 and BZLF1 gene expression, activate latent viruses, and accelerate disease progression by inhibiting HDAC activity ( + T cell accumulation at infection sites and weakening host immunity ( SCFAs have a dual role in regulating inflammation
Thats a chemical problem
For more on how treatment side effects can overlap with normal adjustment, this GLP-1 side effects guide offers useful context
A backup contraceptive method is advisable during dose escalation
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