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Binding studies employed tritiated small molecule HGF analogs to map the distribution of HGF/c-Met receptors in the brain, establishing a correlation with known AT4 receptor densities

One of the hallmarks of incretin drugs in the brain is that they decrease dopamine release but the specific contribution of GIPR signaling alone was unknown

Altunda, D

Tirzepatide is a dual GIP/GLP-1 receptor agonist, meaning it activates both the GLP-1 receptor and the glucose-dependent insulinotropic polypeptide receptor