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PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria

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10.1371/journal.pone.0085322 PLoS One 21 JayarajR.AzimullahS.BeiramR.JalalF.RosenbergG

The IGF-2 receptor only binds IGF-2 and acts as a "clearance receptor"it activates no intracellular signaling pathways, functioning only as an IGF-2 sequestering agent and preventing IGF-2 signaling