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At specified time intervals (0 h, 1 h, 2 h, 4 h, 6 h, 8 h, 12 h, 24 h, 48 h), the sample solution (1.5 mL) was withdrawn from the dialysate, after which an equal volume of fresh corresponding solution (1.5 mL) was promptly added back into the dialysate to maintain the overall volume

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The results showed that the treatment with Ru(II)-OH reduced the tumor volume by 35%, the treatment with NP2 by 66%, and the treatment with NP4 by 91% (Fig

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