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Most older adults dont need a B12 supplement Older adults should not take B12 supplements unless they have a documented deficiency, Yourman says and only about 20 percent of adults over age 60 do, according to a report from the American Academy of Family Physicians

No high-quality clinical trial has demonstrated that B12 injections produce meaningful weight loss outcomes independent of dietary and exercise changes

SIRT1 Activation: Promotes fat oxidation, muscle preservation, and reduced inflammation (Price et al., Cell Metabolism )