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All mice were housed under specific pathogen-free (SPF) conditions with 12 h light/12 h dark cycle at 2124 C, and humidity at 4060%, and were fed with a standard chow diet at the Laboratory Animal Center of the Sixth Affiliated Hospital, Sun Yat-sen University

The beginning of the linker forms a disulfide bond with the main body of SRCR2 (C176-C238), which may be further stabilised by a salt bridge between R183 and E239 (Fig

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Every production batch undergoes comprehensive analytical verification using HPLC peptide analysis and LC-MS testing to support purity, identity, consistency, and reproducibility for laboratory research

This decides that monthly B12 injections should move to optimal 2 monthly frequency