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In patients with alcohol dependence and delirium unresponsive to high doses of benzodiazepines, alcoholic pellagra should be considered, since chronic alcoholism leads to a lack of tryptophan 2,3-dioxygenase, an enzyme linked to niacin synthesis

(2004) "Inhibition of ghrelin action by an RNA-based GHS-R antagonist." Published in PNAS

If the amount of acetaminophen exceeds the capacity of the liver for sulfation, it then utilizes the UGT genes for glucuronidation reactions, which also makes the acetaminophen more water-soluble and able to be excreted

Signs and symptoms of vitamin B12 deficiency can include fatigue, pale skin, headaches, shortness of breath, fast heartbeat, gastrointestinal issues, mouth inflammation, paresthesias (abnormal sensations), decreased cognitive ability, depression, muscle weakness, imbalance and incoordination, vision problems, and erectile dysfunction

It is theorized to act by binding to the ghrelin receptor, also referred to as the growth hormone secretagogue receptor (GHS-R1a)