When consumed in excess amounts, its flushed out of the body through urine
Some of these adverse effects reported were Toxic Epidermal Necrolysis (a rare but life-threatening skin condition characterized by painful blisters and large areas of skin peeling), air embolism, thyroid dysfunction, and liver, kidney, and neurologic toxicity (The dark side of skin lightening- PubMed) With the proliferation of med-spas in an unregulated fashion, there is a risk of inadequately trained or untrained people giving IV injections in a non-sterile way, which can lead to sepsis and transmission of infections like HIV and hepatitis
Witkowski et al., 2020)
and Zeljko Djakovics 51 study which demonstrated that the fistula formed after esophagogastric anastomosis in rats could be cured by BPC 157 and aggravated by L-NAME
As a free radical, it can modify numerous cellular components, as described above ( NO may bind to soluble guanylate cyclase (SGC), which, when activated, regulates the contraction of smooth muscle