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We also observed that mean enrichment of a substrate decreases monotonically with increasing Hamming distance to procaspase-1, consistent with our hypothesis that cleavage activity on single-residue substitutions is predictive of cleavage activity on higher-order combinations of substitutions (Supplementary Fig
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TAS was significantly higher in SHR from the age of 3 weeks when compared with age-matched WKY rats (Table 3)
Of particular clinical importance with retatrutide is its glucagon receptor agonism
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