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GW, FK, TG, and JM designed the experiments and wrote the manuscript
System X(c) (-)/GSH/GPX4 axis: An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy
The Bottom Line Glutathione is indeed a remarkable compound with profound effects on aging and overall health
Trx and GSH/Grx systems are distributed in the cortex, striatum, hippocampus, etc., and play crucial roles in the cellular defense against oxidative stress in hypoxia-induced ischemic injury
(PubMed) Yang J, Wang T, Yang J, et al
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