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Stimulating GLP-1 Production Through Diet Studies of the Mediterranean diet show that the combination of lean protein, healthy fats, and dietary fiber-rich foods stimulate high levels of GLP-1 after meals (compared to a high-fiber vegetarian diet) 6
The retatrutide phase 2 data, showing up to approximately 24.2% mean weight loss at 48 weeks with the 12 mg dose, suggests that the triple agonist mechanism may offer incremental benefit over dual agonism
At the maximum 15mg dose, average weight loss reached 22.5%
Available: [40] Pharmacology Rounds: GLP-1 Receptor Agonists Part 2, EM:RAP
Eur J Endocrinol 183(5):R119R132 Yamada C, Yamada Y, Tsukiyama K, Yamada K, Udagawa N, Takahashi N, Tanaka K, Drucker DJ, Seino Y, Inagaki N (2008) The murine glucagon-like peptide-1 receptor is essential for control of bone resorption
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