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Methods We established lenvatinib-sensitive/lenvatinib-resistant (LS/LR) HCC models and employed multi-omics (proteomics/RNA-seq), chromatin immunoprecipitation, luciferase, and RNA immunoprecipitation assays to map hexokinase domain containing protein 1 (HKDC1) regulation

Symptoms included malaise, myalgias, respiratory distress, somnolence, and abdominal pain

Intragastric butyrate decreased food intake, whereas intravenous injection did not lead to any changes

This could be taken as evidence that gastric emptying was similar for both groups, however, we obtained blood glucose levels 1 and 3 h post drinking

These studies highlight the importance of continued treatment for sustained success